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Bristol-Myers Squibb Company (BMY) 2024 10-K Earnings Analysis

By DouyaLast reviewed: 2026-04-25How we score

Bristol-Myers Squibb Company2024 Earnings Analysis

BMY|US|Quality · Moat · Risks
C

72/100

Bristol Myers Squibb's FY2024 is a patent-transition story disguised as a GAAP loss: $48.3B revenue, a reported -$8.95B net loss after Karuna and RayzeBio acquisition charges, but $13.9B of free cash flow from the underlying portfolio. Eliquis and Opdivo still fund the enterprise, while Camzyos, Cobenfy, Reblozyl and other newer assets are being asked to bridge the Revlimid decline. The real analytical task is to separate temporary purchase-accounting noise from the harder question of whether the replacement portfolio can scale quickly enough.

Filing analysis

Bristol-Myers Squibb Company 2024 10-K Analysis

This page reads Bristol-Myers Squibb Company's 2024 10-K annual report through the EarningsMoat framework: earnings quality, economic moat strength, capital allocation, and key risks. The current overall score is 72/100, or grade C.

BMY Earnings Quality

The earnings-quality module scores 72/100, with Gross Margin: 71.1%, Reported Net Loss: -$8.95B. The core question is whether reported profit is backed by operating cash flow and recurring business economics. See the earnings quality analysis guide.

BMY Economic Moat Analysis

The moat-strength module scores 76/100, with Eliquis Franchise: Anticoagulant leadership, Oncology IO Portfolio: Opdivo, Opdualag. The test is whether the advantage can protect returns after competitors react. Read the economic moat analysis guide.

BMY Free Cash Flow vs Net Income

CF/Net Income (skewed): N/M is the fastest read on whether accounting earnings turn into cash. The capital-allocation module scores 78/100. For the diagnostic, start with cash flow vs net income.

BMY Key Risks from the Annual Report

The risk module scores 62/100, with Revlimid LOE: Staggered generic entry, IRA Drug Pricing: Eliquis selected. The goal is to separate ordinary disclosure from risks that can change margins, cash flow, leverage, or the moat itself.

Is BMY a High Quality Earnings Stock?

Based on this 2024 filing, BMY needs a closer read before it qualifies as a high-quality earnings candidate: the overall grade is C, and the earnings-quality score is 72/100. This is a research screen, not investment advice.

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Core Dimension Scores

Evaluating competitive strength across earnings quality, moat strength, and risk sustainability

Earnings Quality
72/100
Earnings quality scores 72/100. BMS's FY2024 GAAP loss does ...
Moat Strength
76/100
Moat strength scores 76/100. BMS's moat today is less about ...
Capital Allocation
78/100
Capital allocation scores 78/100. BMS is deploying cash the ...
Key Risks
62/100
Risk profile scores 62/100 (higher = safer). Per the FY2024 ...

Overall Score Trend

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Earnings Quality

72/100
Gross Margin
71.1%

Per the FY2024 10-K income statement, gross margin of 71.1% is consistent with a branded-pharma business. The margin is insulated from the IPRD write-off that falls below the gross-profit line.

Reported Net Loss
-$8.95B

Per the FY2024 10-K income statement, net loss of $8.95B reflects approximately $12B+ in acquired-IPRD (in-process research and development) charges — non-cash purchase-accounting items disclosed in the acquisition footnote for the Karuna Therapeutics and RayzeBio transactions closed in 2024.

CF/Net Income (skewed)
N/M

Per the FY2024 cash flow statement, OCF of $15.2B contrasts with the -$8.95B reported NI. The apparent negative CF/NI ratio is a consequence of the IPRD write-off not affecting cash; OCF is the cleaner read of underlying earning-power for the period.

Revenue Mix
Growth portfolio shift

Per the FY2024 MD&A, revenue composition is shifting from Revlimid (post-loss-of-exclusivity and going through staggered generic entry per the Celgene-heritage settlement) toward the growth portfolio — Eliquis (anticoagulant), Opdivo (IO), Opdualag, Reblozyl, Camzyos, Breyanzi, Cobenfy (post-Karuna), plus the pipeline.

Earnings quality scores 72/100. BMS's FY2024 GAAP loss does not describe the operating business very well, because acquired-IPRD charges from the 2024 M&A wave overwhelmed the income statement. The cleaner read is still the cash statement: this is a large biopharma franchise generating substantial cash while simultaneously digesting a patent cliff and trying to accelerate the next product set.

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Moat Strength

76/100
Eliquis Franchise
Anticoagulant leadership

Per the FY2024 product-revenue disclosures, Eliquis (apixaban, co-developed with Pfizer per the partnership agreement) is the largest revenue product line. The anticoagulant category has a disclosed Medicare Drug Price Negotiation exposure under the IRA framework — Eliquis is on the first list of selected drugs per HHS public announcements.

Oncology IO Portfolio
Opdivo, Opdualag

Per the FY2024 10-K product disclosures, BMS's oncology portfolio includes Opdivo (PD-1 immuno-oncology), Opdualag (PD-1/LAG-3 combo), Breyanzi (CAR-T), Abecma (CAR-T with partner 2seventy bio per the partnership), Reblozyl (anemia). The IO portfolio has broad indication coverage per the publicly-approved label extensions.

New Product Wave
Growth portfolio

Per the FY2024 MD&A and product-launch press releases, the growth portfolio includes Camzyos (HCM cardiomyopathy), Cobenfy (schizophrenia via the Karuna acquisition per the closing press release), Sotyktu (psoriasis), Reblozyl, and Opdualag. Management frames these as the post-Revlimid revenue-bridge trajectory.

Goodwill/Assets
23.5%

Goodwill of $22B on $93B assets equals 23.5% per the FY2024 balance sheet — reflecting principally the 2019 Celgene acquisition (~$74B per the closing press release) plus the 2024 Karuna and RayzeBio acquisitions. Note that goodwill is separate from the IPRD charges that hit the income statement.

Moat strength scores 76/100. BMS's moat today is less about one unbeatable franchise and more about whether a broad oncology-and-immunology portfolio can successfully hand the baton from older blockbusters to newer growth assets. Eliquis and Opdivo still matter enormously, but the durability case now depends on portfolio replacement discipline, not on endless life-cycle extensions of one or two legacy products.

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Capital Allocation

78/100
Free Cash Flow
$13.9B

Per the FY2024 cash flow statement, FCF of $13.9B (OCF $15.2B minus capex $1.25B) supports the dividend (raised multiple times per the dividend-history disclosure) plus debt reduction and pipeline investment.

2024 M&A Wave
Karuna + RayzeBio

Per Bristol Myers Squibb's 2024 Karuna Therapeutics closing press release (approximately $14B transaction) and RayzeBio closing press release, the two transactions added Cobenfy (muscarinic-receptor-agonist for schizophrenia) and radiopharmaceutical-platform assets. The combined $12B+ IPRD write-off reflects the early-stage value allocation.

Dividend Record
Multi-decade

Per the FY2024 dividend-history disclosure and BMS's quarterly-dividend announcement press releases, the company has maintained and periodically raised the dividend across many decades.

Debt Position
Elevated

Per the FY2024 balance sheet, interest-bearing debt of $51.5B against $10.3B cash is elevated — a residual from the Celgene acquisition financing plus the 2024 Karuna and RayzeBio transactions. The $13.9B FCF supports service capacity and disclosed deleveraging targets in investor-day materials.

Capital allocation scores 78/100. BMS is deploying cash the way a large pharma facing a patent transition usually must: defend the dividend, manage leverage, and use M&A to pull forward replacement revenue. That makes the capital-allocation file look more urgent than Gilead's. The issue is not capacity, because the cash flow is there; it is whether management is buying the right bridge assets at the right price.

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Key Risks

62/100
Revlimid LOE
Staggered generic entry

Per the FY2024 Revlimid-revenue disclosure and the Celgene-era settlement agreement disclosed in prior 10-Ks, Revlimid (lenalidomide, for multiple myeloma) has entered a multi-year staggered generic-entry period that compresses product revenue through FY2025-26.

IRA Drug Pricing
Eliquis selected

Per HHS CMS's public announcements under the Inflation Reduction Act, Eliquis is among the first 10 Medicare Part D drugs selected for negotiation with maximum fair prices effective January 1, 2026 per the CMS disclosure. The pricing impact is the principal long-term revenue-compression exposure.

Pipeline Execution
Critical

Per the FY2024 Risk Factors, successful launch and label expansion of the growth-portfolio products (Camzyos, Cobenfy, Opdualag, Reblozyl) plus pipeline-asset-progression (including Karuna-origin KarXT now Cobenfy label expansions and RayzeBio radiopharmaceutical candidates) is the principal revenue-replacement pathway.

Debt Stack
$51.5B

Per the FY2024 balance sheet, $51.5B of interest-bearing debt is elevated relative to pre-Celgene-acquisition levels. Service depends on sustained FCF generation; a prolonged new-product-uptake disappointment would compress deleveraging cadence.

Risk profile scores 62/100 (higher = safer). Per the FY2024 10-K, the principal watch-items are (1) the Revlimid LOE-driven staggered generic-entry revenue compression per the Celgene-era settlement, (2) Eliquis Medicare IRA drug-price-negotiation exposure (selected on the first list per HHS CMS disclosures, effective 2026), (3) new-product-launch execution on Camzyos/Cobenfy/Opdualag/Reblozyl as the revenue-replacement pathway, and (4) the $51.5B debt stack from Celgene + 2024 M&A financing whose deleveraging depends on FCF generation.

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Management

Facts · No Score
CEO: Chris Boerner
Per the FY2024 proxy and BMS's October 2023 leadership-transition announcement, Chris Boerner became CEO in November 2023 after previously serving in commercialization and portfolio leadership roles. That matters because the current BMS challenge is commercial execution on the replacement portfolio as much as it is scientific output.
Karuna Acquisition
Per BMS's March 2024 Karuna Therapeutics closing press release, BMS completed the approximately $14B acquisition of Karuna, bringing in KarXT (xanomeline/trospium) — subsequently FDA-approved as Cobenfy for schizophrenia in September 2024 per the FDA-approval press release. The IPRD allocation of the deal flowed through the FY2024 income statement as a non-cash charge.
RayzeBio Acquisition
Per BMS's February 2024 RayzeBio closing press release, BMS completed the acquisition of RayzeBio to add actinium-based radiopharmaceutical platform and pipeline assets. The transaction follows the disclosed M&A framework of targeted-oncology-modality expansion.
Cost-Reduction Plan
Per BMS's 2024 strategic-productivity-initiative communications and the FY2024 MD&A, management has publicly targeted multi-year cost reductions through operational efficiency and R&D prioritization. Execution cadence is disclosed in quarterly earnings reports.

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This analysis is for educational purposes only and does not constitute investment advice.